Enhanced recovery after surgery (ERAS) for ovarian cancer – a sytematic review to identify candidate interventions — YRD
  1. Schedule
  2. Session 5
  3. Enhanced recovery after surgery (ERAS) for ovarian cancer – a sytematic review to identify candidate interventions

Enhanced recovery after surgery (ERAS) for ovarian cancer – a sytematic review to identify candidate interventions (2630)

Kristina Lindemann 1 2 3 , Peey-Sei Kok 1 2 , Martin Stockler 1 , Ken Jaaback 4 , Alison Brand 2 5
  1. NHMRC Clinical Trials Centre, Camperdown, NSW, Australia
  2. Australian New Zealand Gynecological Oncology Goup (ANZGOG), Camperdown, NSW
  3. Crown Princess Mary Cancer Centre, Westmead, NSW
  4. Department of Gynaecological Oncology, John Hunter Hospital, Newcastle, NSW
  5. Department of Gynaecological Oncology, Westmead Hospital, Westmead, NSW

Objective: To summarize the evidence of ERAS interventions in ovarian cancer.

Methods: MEDLINE/Cochrane Library were systematically searched for studies ≥1 ERAS interventions in ovarian cancer patients. Studies were included irrespective of design and references were hand reviewed for completeness.

Results: Of 23 studies, nine observational studies reported on complete ERAS protocols. Fourteen studies reported on single interventions e.g. early feeding, omission of pelvic drains, early orogastric tube removal, doppler guided fluid management, and patient-controlled epidural anaesthesia. Most of the 10 randomized controlled trials studied early feeding protocols.

Conclusion: Most studies including ovarian cancer patients were susceptible to bias. The strongest evidence exists on early feeding protocols, however, definition of early feeding varied. The larger scope of surgery and patients’ comorbidities challenge the extrapolation of evidence of ERAS from other surgical disciplines. We propose an innovative randomised trial to determine the feasibility, safety and effectiveness of ERAS in ovarian cancer.