Australia's first gestational trophoblastic disease registry was established in 1978 following a visit by Professor Ken Bagshawe from Charing Cross Hospital, London, in 1978. Establised at The Royal Women's Hospital,  Dr Alynn Long was the first director and was succeeded by Prof Michael Quinn in 1983. A database "HyMol"was developed in early to support the registry. For the last seven years A/Professor Orla McNally has been the director supported by the multi-disciplinary gynae-oncology team.

The presentation will provide an overview of the registry over the last almost 40 years and the current challenges often presented in the management of this extraordinary condition.