Minor Clear Cell and Serous Components in Stage 1, Grade 1/2 Endometriod Adenocarcinomas; Do They Affect Prognosis? — YRD
  1. Schedule
  2. Session 2
  3. Minor Clear Cell and Serous Components in Stage 1, Grade 1/2 Endometriod Adenocarcinomas; Do They Affect Prognosis?

Minor Clear Cell and Serous Components in Stage 1, Grade 1/2 Endometriod Adenocarcinomas; Do They Affect Prognosis? (2894)

Nimithri Cabraal 1
  1. Gold Coast University Hospital, Biggera Waters, QLD, Australia

Background

Minor components of clear and serous type carcinomas are reportedlyfound in otherwise low grade endometriod type adenocarcinomas. The WHO recommends that any percentage greater than 5% be reported and that this may affect patient prognosis

Objectives

To determine the percentage of minor componenets of clear cell and serous carcinomas in otherwise low grade endometriod carcinomas and to also determine whether the presence of minor components of clear cell and serous carcinoma adversely affect outcomes

Method

A list of stage 1 endometrial adenocarcinoma patients presented at Tumour Board at John Hunter Hospital between 2006 and 2010 was obtained. Chart and slide review was undertaken for patients that met selection criteria. The presence and percentage of clear cell or serous components was recorded where found and subsequently further immunohistochemistry (IHC) was performed

Results

100 cases were reviewed. 18 had identifiable clear or serous like components. IHC did not support a diagnosis of clear or serous components in any case. Prognosis did not appear to be adversely affected by the presence of these components.